Ketamine Infusions for PTSD and Treatment Resistant Depression | Northern Virginia Ketamine Infusion Center 22306

NOVA Health Recovery Ketamine Infusion Center offers Ketamine infusions for Depression, Anxiety, PTSD, Chronic pain. We use intravenous and oral ketamine along with ketamine assisted psychotherapy (KAP) to treat multiple mood disorders. Northern Virginia Ketamine | Contact us below by email and leave your phone number as well, or call 703-844-0184 for an immediate appointment.

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                        Ketamine for PTSD and co-occurring depression 

A study linked above demonstrated the effective use of 6 ketamine infusions in veterans with comorbid PTSD and treatment resistant depression. 

Total number of patients: 15 

Six Ketamine infusions received Monday, Wednesday, Friday over two weeks at doses of 0.5 mg/kg over 40 minutes. 

Data using the PTSD score and Montgomery-Asberg Depression Rating Scale score of depression which was collected before treatment, 24 hours later, and then weekly for 8 weeks. 

Results: The remission rate for PTSD was 80.0%, and the response rate for TRD was 93.3%. Participants in remission from PTSD after the infusion series (n = 12) had a median time to relapse of 41 days. Similarly, participants whose depression symptoms responded to the infusion series (n = 14) had a median time to relapse of 20 days

Generally, antidepressants such as SSRIs are used to treat PTSD and TRD (treatment resistant depression) and only 36.8% of patients with MDD remit with the first antidepressant used per STAR*D trial dataTreatment of PTSD with SSRIs leaves abundant residual symptoms as well. Ketamine does not worsen acute stress in PTSD patients. 

Multiple trials have demonstrated efficacy of ketamine in MDD (Major Depressive Disorder): 

  1. The antidepressant effects of ketamine 
  1. A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression 
  1. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. 
  1. A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression 
  1. Replication of ketamine’s antidepressant efficacy in bipolar depression: a randomized controlled add-on trial 

The trajectory of treatment in the above single dose ketamine studies demonstrated a positive response at 24 hours that declined over 7-14 days. 

Although comorbid PTSD and MDD occur together, there are few effective treatments for either. The trial referenced in this article attempts to intervene on patients who have FAILED two antidepressant medications. 

One study in ketamine therapy of chronic PTSD demonstrated a rapid and significant reduction in symptoms. 

Other studies have demonstrated that repeat ketamine infusions have prolonged improvements of mood in MDD and TRD. 

Serial Ketamine studies with links are below: 

  1. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression 
  1. Rapid and longer-term Antidepressant effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression 
  1. Serial infusions of low-dose ketamine for major depression 
  1. Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment resistant depressio

Other trials of ketamine in PTSD

  1. Feder et al: Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress DisorderA Randomized Clinical Trial  This was the first randomized trial of ketamine for PTSD. The findings demonstrated a greater reduction of PTSD symptoms following treatment with ketamine was evident in both crossover and first-period analyses, and remained significant after adjusting for baseline and 24-hour depressive symptom severity. Ketamine was also associated with reduction in comorbid depressive symptoms and with improvement in overall clinical presentation. There was a single ketamine infusion of 0.5 mg/kg infused over 40 minutes. The effects lasted up to 7 days. 
  1. Efficacy, Safety, and Durability of Repeated Ketamine Infusions for Comorbid Posttraumatic Stress Disorder and Treatment-Resistant Depression The remission rate for PTSD was 80.0%, and the response rate for TRD was 93.3%. Participants in remission from PTSD after the infusion series (n = 12) had a median time to relapse of 41 days. Similarly, participants whose depression symptoms responded to the infusion series (n = 14) had a median time to relapse of 20 days. Repeated ketamine infusions were associated with transient increases in dissociative symptoms. No participant reported worsening of PTSD symptoms over the study duration. 
  1. Impact of oral ketamine augmentation on hospital admissions in treatment-resistant depression and PTSD: a retrospective study  Oral doses of 0.5 mg/kg up to 7 mg/kg were used in a retrospective study and demonstrated inpatient hospital days were reduced by 70%, and hospital admissions were reduced by 65%. 
  1. The correlation between ketamine and posttraumatic stress disorder in burned service members  Perioperative soldiers who received ketamine had a 27% incidence of PTSD versus 49% of those who did not. 

A further recent review of ketamine for PTSD is linked HERE and HERE 

Ketamine with exposure-based therapy also represents an option to augment its treatment effects. Trials are ongoing regarding this option. 

What are the standard therapies for PTSD? 

  • Psychotherapy 
  • EMDR 
  • Exposure-based therapies 
  • FDA Approved SSRI’s for PTSD 
  • Atypical antipsychotics such as quetiapine and risperidone. 
  • Prazosin for nightmares and insomnia 
  • Benzodiazepines such as valium  

Ketamine therapy appears to be an effective adjunct treatment for PTSD. 

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NOVA Health Recovery is a Ketamine Treatment Center in Fairfax, Virginia (Northern Virginia Ketamine) that specializes in the treatment of depression, anxiety, bipolar disorder, OCD, and chronic pain such as CRPS, cluster headaches, and fibromyalgia using Ketamine therapies, both infusion and home-based ketamine nasal spray and oral tablets. We also offer addiction treatment services with Suboxone, Vivitrol, and Sublocade therapies for opiate addiction as well as alcohol treatment regimens. Contact us at 703-844-0184 or at this link: NOVA Health Recovery Ketamine Infusion Center Near me Ketamine Infusion 

Ketamine Provider | Ketamine near me | Psychedelic assisted therapy | Mushrooms | Ketamine assisted psychotherapy | Ketamine psychedelic therapy | KAP | K hole | New depression Treatments | Areas we serve: 

Maryland (MD): 

Bethesda 20814 – Bethesda 20816 – Bethesda 20817 – Chevy Chase 20815 – Colesville 20904 – Cabin John 20815 – Glen Echo 20812 – Gaithersburg 20855 – Gaithersburg 20877- Gaithersburg 20878 – Gaithersburg 20879 – Garrett Park 20896 – Kensington 20895 – Montgomery Village 20886 – Olney 20830 – Olney 20832 – Potomac 20854 – Potomac 20859 – Rockville 20850 – Rockville 20852 – Rockville 20853 – Silver Spring 20903 – Silver Spring 20905 – Silver Spring 20906 – Silver Spring 20910 – Takoma Park 20912 – Wheaton 20902 

Washington DC: 

Crestwood 20011- North Capitol Hill 20002 – Cathedral Heights 20016 – American University Park 20016 – Columbia Heights 20010 – Mount Pleasant 20010 – Downtown 20036 – Dupont Circle 20009 – Logan Circle 20005- Adams Morgan 20009 – Chevy Chase 20015 – Georgetown 20007 – Cleveland Park 20008 – Foggy Bottom 20037 – Rock Creek Park – Woodley Park 20008 – Tenleytown 20016 

Northern Virginia: 

McLean 22101- McLean 22102 – McLean 22106 – Great Falls 22066 – Arlington 22201 – Arlington 22202 – Arlington 22203 – Arlington 22205 – Falls Church 22041 – Vienna 22181 – Alexandria 22314 – 22308 -22306 -22305 -22304  Fairfax – 20191 – Reston – 22009 – Springfield – 22152  22015  Lorton 22199 

Fairfax, Va 

2303 –  22307 – 22306 – 22309 – 22308 22311 – 22310 – 22312 

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Springfield – 22150 – 22151 -22152-22153-22154-22155 -22156 – 22157 -22158 -22159 -22160 – 22161  

Front Royal 22630 

Warren County 22610 22630 22642 22649 

Fredericksburg Va 22401 22402 – 22403 – 22404 -22405 -22406 -22407 -22408 – 22412  

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20108 Manassas Manassas City 20109 Sudley Springs Prince William County 

20109 Manassas Prince William County 20110 Manassas Manassas City 

20111 Manassas Prince William County 20111 Manassas Park Prince William County 

20112 Manassas Prince William County 20113 Manassas Park Manassas Park City 

20115 Marshall Fauquier County 20116 Marshall Fauquier County 

20117 Middleburg Loudoun County 20118 Middleburg Loudoun County 

20119 Catlett Fauquier County – 20120 Sully Station Fairfax County 

20120 Centreville Fairfax County – 20121 Centreville Fairfax County 

20122 Centreville Fairfax County – 20124 Clifton Fairfax County 

20128 Orlean Fauquier County -20129 Paeonian Springs Loudoun County 

20130 Paris Clarke County 

20131 Philomont Loudoun County 20132 Purcellville Loudoun County 

20134 Hillsboro Loudoun County 20134 Purcellville Loudoun County 

20135 Bluemont Clarke County 20136 Bristow Prince William County 

20137 Broad Run Fauquier County 20138 Calverton Fauquier County 

20139 Casanova Fauquier County 20140 Rectortown Fauquier County 

20141 Round Hill Loudoun County 20142 Round Hill Loudoun County 

20143 Catharpin Prince William County 

20144 Delaplane Fauquier County20146 Ashburn Loudoun County 

20147 Ashburn Loudoun County 20148 Brambleton Loudoun County 

20148 Ashburn Loudoun County 20151 Chantilly Fairfax County 

20151 Fairfax Fairfax County 20152 South Riding Loudoun County 

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20158 Hamilton Loudoun County 20159 Hamilton Loudoun County 

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20167 Sterling Loudoun County 20168 Haymarket Prince William County 

20169 Haymarket Prince William County 20170 Herndon Fairfax County 

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20172 Herndon Fairfax County 20175 Leesburg Loudoun County 

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20180 Lovettsville Loudoun County 20181 Nokesville Prince William County 

20182 Nokesville Prince William County 20184 Upperville Fauquier County 

20185 Upperville Fauquier County 20186 Warrenton Fauquier County 

20187 New Baltimore Fauquier County 20187 Vint Hill Farms Fauquier County 20187 Warrenton Fauquier County 

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20190 Reston Fairfax County 20190 Herndon Fairfax County 

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20197 Waterford Loudoun County 20198 The Plains Fauquier County 

Loudon County: 

Loudoun County, VA – Standard ZIP Codes 

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Ashburn, VA – Standard ZIP Codes 

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